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The name 'Amphigastropoda' has been used for an assemblage of planispiral or cap-shaped, mostly Palaeozoic molluscs. Primarily centered around the Bellerophontoidea, other groups that have been included in the Amphigastropoda by various authors include the Pelagielliformes, Cyrtolitidae and Tryblidiidae. The grouping was originally proposed on the basis that these animals were gastropod-like but untorted; however, studies of muscle scars the genus Bellerophon itself indicate that it, at least, underwent torsion, and the Amphigastropoda in the broad sense is probably a polyphyletic assemblage (Peel 1972).
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. Observations on some Lower Palaeozoic tremanotiform Bellerophontacea (Gastropoda) from North America. Palaeontology 15 (3): 412-422.
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A. The surgery is actually quite simple and straightforward for both types of devices: It is a one-hour, outpatient procedure. Even the most complex hydraulic devices are inserted through a two-inch incision in the scrotum. For the malleable implants, a pair of silicone rods are implanted in the corpora cavernosa. While it's a less serious operation than a radical prostatectomy, there is much more postsurgical discomfort associated with penile implant surgery. This pain, bruising and soreness can last for weeks and patients typically must take 10 days to two weeks off work until the area has healed.
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Selective enzyme inhibitors are available by prescription and may be taken up to once a day to treat ED. They improve partial erections by inhibiting the enzyme that facilitates their reduction and increase levels of cyclic guanosine monophosphate (cGMP, a chemical factor in metabolism), which causes the smooth muscles of the penis to relax, enabling blood to flow into the corpora cavernosa.
A urinalysis looking for RBCs, WBCs, protein, and glucose is also important.
This work was supported by National Institutes of Health Grant DK21723 (to J.B.) and the University of Washington Cardiovascular Pathology Training Grant NIH HL-07312 (to A.B.).
By Steven Reinberg
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Should men be checked for infertility?
The Pittsburgh team found that the genes for the "glial cell line derived neurotrophic factor" (GDNF) and the GDNF family ligand, called neurturin, were both effective in treating erectile dysfunction in the rats. The genes were placed in a genetically engineered herpes simplex virus, which was then injected into the rats' damaged cavernous nerve.
A number of specialized investigations exist for the evaluation of erectile dysfunction but need not be part of the routine evaluation. The penile brachial index involves measuring penile pressure and comparing it with arm pressure. It has limited clinical utility because the data are based on superficial and deep penile arterial pressure, whereas erectile function depends on the deep arteries exclusively. Duplex ultrasonography allows for refined assessment of the penile circulation. The information it provides, however, is operator dependent and rarely alters patient management. Selective pudendal arteriography combined with intracavernous injection of a vasoactive drug should be limited to the small group of patients who are candidates for penile revascularization surgery. These patients include nonsmoking men less than 40 years old with a history of pelvic trauma who have sustained a penile arterial disruption.30
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For example, some studies have shown that chemicals released from muscle proteins when they're cooked at high temperatures could increase risk of prostate cancer in some, Mason said.
ED can in many cases be treated by drugs taken orally, injected, or as penile suppositories. These drugs increase the efficacy of nitrous oxide, which dilates the blood vessels of corpora cavernosa. When oral drugs or suppositories fail, injections into the erectile tissue of the penile shaft are extremely effective but occasionally cause priapism.
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