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Polychaeta The "many-bristled ones"


, a worm


The Polychaeta or Polychaetes are a class of worms, generally marine, with a pair of fleshy protrusions on each body segment called that bear many bristles, called setae, which are made of . Polychaeta means "many-bristled" (as opposed to the which are "few-bristled"), and indeed the polychaetes are sometimes referred to as bristle worms. More than 10,000 are described in this class, but common representatives are the (Arenicola marina) and the or Nereis.

The polychaetes' paddle-like and highly vascularized parapodia are used for movement and act as the animal's primary surfaces (parapodia can be thought of as kinds of external that are also used for locomotion). Polychaeta also have well-developed heads compared to other annelids.

Taxonomically, the polychaetes are now known to be , meaning that as a group it contains its most recent common ancestor, but does not contain all the descendants of that ancestor. In other words they represent an evolutionary of worlm-like animals.

Polychaetes are extremely variable in both form and lifestyle and include a few taxa that swim among the . Most burrow or build tubes on or in the bottom, and some live as commensals. A few are parasitic. The mobile forms tend to have well-developed sense organs and jaws, while the stationary forms lack them but may have specialized gills or tentacles used for respiration and deposit or filter feeding, e.g., .

One notable polychaete, the (Alvinella pompejana) is to the of the . Pompeii worms are thought to be the most heat-tolerant complex animals known.

is a that reaches lengths of over 3 meters and may be the most long lived animal at over 250 years old.

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Penile Implants Penile implants involve surgical insertion of malleable or inflatable rods or tubes into the penis. A semi-rigid prosthesis is a silicon-covered flexible metal rod. Once inserted, it provides the rigidity necessary for intercourse and can be curved slightly for concealment. It requires the simplest surgical procedure of all the prostheses. Its main disadvantage is that concealment can be difficult with certain types of clothing. Restless Legs Linked to Erectile Dysfunction Insurance coverage of ED depends upon the type of treatment prescribed. If there is a documented medical condition that is shown to be causing ED, insurance will usually cover at least some of it. Sex therapy and medications that have not yet been approved by the FDA, however, are generally not covered. Talk to your insurance provider to determine if the treatment you are considering will be covered. ED treatment drugs have a high placebo response: if a good result is expected, any highly praised, and often expensive, treatment can be effective. Reputable drugs can also benefit from the same effect. Click 28.5 percent of the patients had a history of diabetes, 18.8 percent had heart disease, 37.2 percent had tried Viagra, and 7.5 percent were receiving both Uprima and nitrate therapy for angina. Cyclic nucleotide phosphodiesterases (PDEs) are enzymes that regulate the cellular levels of the second messengers, cAMP and cGMP, by controlling their rates of degradation. There are 11 different PDE families, with each family typically having several different isoforms and splice variants. These unique PDEs differ in their three-dimensional structure, kinetic properties, modes of regulation, intracellular localization, cellular expression, and inhibitor sensitivities. Current data suggest that individual isozymes modulate distinct regulatory pathways in the cell. These properties therefore offer the opportunity for selectively targeting specific PDEs for treatment of specific disease states. The feasibility of these enzymes as drug targets is exemplified by the commercial and clinical successes of the erectile dysfunction drugs, sildenafil (Viagra), tadalafil (Cialis), and vardenafil (Levitra). PDE inhibitors are also currently available or in development for treatment of a variety of other pathological conditions. In this review the basic biochemical properties, cellular regulation, expression patterns, and physiological functions of the different PDE isoforms will be discussed. How these properties relate to the current and future development of PDE inhibitors as pharmacological agents is especially considered. PDEs hold great promise as drug targets and recent research advances make this an exciting time for the field of PDE research. However it is believed that old people are more likely to suffer from sexual problems like erectile dysfunction or ED. Erectile Dysfunction is a sexual problem that occurs in males under which he is unable to get penis erection for an amount of time essential for indulging in satisfactory sexual intercourse. ED can be a result of various causes which are broadly classified as physical and psychological. The bottom line: Whatever it takes, experts say don't shut down the line of emotional communication, even if you have to put your physical relationship on hold. And most importantly, listen to your heart. Older age, as well as poor sexual function prior to radiation, did increase the risk for sexual impairment after radiation treatment, the researchers said. However, they report no appreciable difference in sexual function between the men receiving the shorter course/higher dose regimen or the more conventional regimen. May only help with marginal penile blood FPRIVATE "TYPE=PICT;ALT=diaphragm - cervical cap" A measurement of luteinizing hormone (LH) and, in some instances, prolactin, may be helpful. A serum prolactin level is obtained if the patient has evidence of pituitary hyperfunction, a common endocrine cause of erectile dysfunction (ED), and in documented cases of low serum testosterone levels. LH levels vary according to the body's need for testosterone. The hypothalamus regulates testosterone levels by releasing or inhibiting LH-releasing hormone, which acts in the pituitary to produce LH. A high LH level associated with a low testosterone level implies primary testicular (Leydig cell) failure. Conversely, a low LH level associated with a low testosterone level suggests a central defect. However, "The distance between biomedical specialties that might once have been bridged mainly by researchers and specialized clinicians now is negotiated mainly by the patients themselves, since their knowledge sets expand and intertwine over time," she wrote. The cyclic nucleotide phosphodiesterases (PDEs1) described in this review are a family of related phosphohydrolases that selectively catalyze the hydrolysis of the 3? cyclic phosphate bonds of adenosine and/or guanosine 3?,5? cyclic monophosphate. The structure of cAMP and the bond hydrolyzed is shown in Fig. 1. These enzymes are often referred to as class I cyclic nucleotide PDEs to differentiate them from class II enzymes. Class II enzymes are found in many species including mammals and will also catalyze the hydrolysis of the phosphodiester bond. However, in general, the Class II enzymes do not show the same substrate selectivity as the class I enzymes and much more is known about the class I enzymes. propecia In the current study, Horwitz and his colleagues tracked the IMRT radiation treatment outcomes of 155 men diagnosed with intermediate to high-risk prostate cancer. Uncontrolled, potentially life-threatening abnormal heart rhythms A study published in Psychology of Men and Masculinity (2006) reported the results of an Internet survey of more than 52,000 heterosexual men and women on the topic of penis size, self-image and women's perception of, and satisfaction with, their partners' penis size. The very large sample size permitted researchers to detect the smallest differences among responses. Accepted: 18 October 2006

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