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The results? Though 80% of those using a conventional seat suffered numbness, only 14% of those using the new seat did. Serfas now offers several seat models for street and mountain bikes.
What other treatments for erectile dysfunction are being studied?
Tubal ligation (also called "getting your tubes tied") involves closing off a woman's fallopian tubes so eggs can't travel through them to reach the uterus. A device called Essure can also be used to close off a woman's fallopian tubes. Essure is a metal coil that is inserted into your fallopian tubes by your doctor.
By Steven Reinberg
Keep the lines of communication open.
In fact, many medications have ED as a side effect, but “hypertensive drugs are classically the worst,” says Nehra. However, he emphasizes, you don’t have to endure this side effect. Talk to your urologist about medications that will counter ED without affecting your blood pressure meds.
Diseases and conditions such as diabetes, high blood pressure, heart or thyroid conditions, poor blood flow, depression, or neurologic disorders (such as multiple sclerosis or Parkinson's disease)
Herbal doctors have made a wonder drug for soving your impotence or erectile dysfunction problem. It is known as Vigomax Forte. This formulation is mentioned Kamasutra, The love book of passionate loves.
A useful and simple way to distinguish between physiological and psychological impotence is to determine whether the patient ever has an erection. If never, the problem is likely to be physiological; if sometimes (however rarely), it could be physiological or psychological. The current diagnostic and statistical manual of mental diseases (DSM-IV) has included a listing for impotence.
When administered in vitro, PDE5 inhibition induces apoptosis in colon carcinoma (15) and chronic lymphocytic leukemia cells (16). To determine whether similar effects could be observed in vivo, we used various transplantable mouse tumors, including CT26WT (a colon carcinoma; Fig. 1 A), the more aggressive variant C26GM (Fig. 1 B), TS/A (a mammary adenocarcinoma; Fig. 1 C), and the MCA203 fibrosarcoma (Fig. 1 D). PDE5 inhibitors were administered starting on the day of tumor challenge. Sildenafil and tadalafil significantly delayed tumor outgrowth by 50 to 70% in immune-competent mice, although all mice ultimately died (Fig. S1, available at http://www.jem.org/cgi/content/full/jem.20061104/DC1). Similar results were obtained even if sildenafil treatment was started on day 7 after tumor challenge in the CT26WT model (Fig. S2). The fact that no difference in tumor outgrowth was seen between early versus late administration of sildenafil suggests that PDE5 inhibition does not appreciably affect the early phases of tumor uptake but rather influences the later stages of tumor outgrowth. Because the addition of sildenafil to cultured CT26WT cells did not increase their apoptosis or affect their doubling time (unpublished data), we conclude that sildenafil does not have a direct antitumor effect but rather interferes in host–tumor interactions.
Vacuum constriction devices vary in cost from $300 to $500, depending on the brand and type. The battery-powered versions tend to be more expensive, but also tend to work a little more quickly. Battery-powered devices are especially helpful for men who do not have good hand strength or coordination, or who have arthritis.
Danial E Baker, PharmD
Common adverse effects include headache, flushing, rhinitis, dyspepsia, or indigestion; assess cardiovascular status before use; caution with left ventricular outflow obstruction or conditions aggravated by hypotension; caution with hepatic or renal impairment (decrease dose); may cause prolonged or painful erection; may cause back pain or myalgias
ED can in many cases be treated by drugs taken orally, injected, or as penile suppositories. These drugs increase the efficacy of NO, which dilates the blood vessels of corpora cavernosa. When oral drugs or suppositories fail, injections (e.g. of apomorphine) into the erectile tissue of the penile shaft may work.
There are many underlying physical and psychological causes of erectile dysfunction. Reduced blood flow to the penis and nerve damage are the most common physical causes. Underlying conditions associated with erectile dysfunction include the following:
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A discussion of the results should be conducted, if possible, with the patient and his partner. This educational process allows a review of the basic aspects of the anatomy and physiology of the sexual response. The possible etiology and associated risk factors, such as smoking and the use of various medications, can be reviewed. Treatment options and their benefits and risks should be discussed. This type of dialogue allows the patient and physician to develop a strategy that is most beneficial.
The administration of apomorphine by subcutaneous, oral, and intranasal routes results in variable effects on erectile function and moderate-to-severe adverse effects, primarily nausea and vomiting. A slow-release sublingual formulation has demonstrated erectile enhancement benefits with a significant reduction in adverse effects.
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